Detonite Ampule farming guide
Earth — Cervantes (Sabotage)
Cervantes’ Rotation B resource cache is a reliably documented Detonite Ampule source (~12.2%) and a fast Sabotage to repeat early. Resource caches are reward tables, so a booster and the Steel Path passive don’t affect this particular pickup — for a boosted enemy farm, see the endgame spot.
Boosters don't apply: this spot is a container/deposit pickup, not an enemy drop.
Saturn — Piscinas (Dark Sector Survival, Steel Path)
A Dark Sector Steel Path Survival where Grineer density is high; Detonite Ampule drops from those enemies (it’s in Saturn’s region resource pool), so a Resource Drop Booster, the Steel Path passive and a Nekros loot squad all raise the yield.
Boosters help: this spot relies on enemy drop tables.
Early game
Cervantes on Earth (Sabotage) has a reliably documented Detonite Ampule source: a Rotation B resource cache with roughly a 12.2% chance. That cache is a reward table rather than an enemy drop, so a booster and the Steel Path passive don’t affect it — but as a quick, guaranteed-structure Sabotage (clear the tileset, grab the Rotation B cache, reset) it’s the clearest early source. For a boosted enemy farm, see the endgame spot below.
Mid & late game
Piscinas on Saturn (Dark Sector Survival) is the wiki’s recommended endgame spot, run with a Steel Path squad. Detonite Ampule is in Saturn’s region resource pool, so it drops from the Grineer you kill — meaning a Resource Drop Booster, the Steel Path passive and a Nekros loot squad all stack here, and long Survival rotations pile up kills for the biggest hauls.